Skip Navigation


Hum. Reprod. Advance Access originally published online on July 13, 2006
Human Reproduction 2006 21(11):2930-2934; doi:10.1093/humrep/del269
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
21/11/2930    most recent
del269v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Wright, K.P.
Right arrow Articles by Keefe, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wright, K.P.
Right arrow Articles by Keefe, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

The effect of female tobacco smoking on IVF outcomes

K.P. Wright1,5, J.R. Trimarchi2, J. Allsworth3 and D. Keefe4

1 Department of Obstetrics and Gynecology 2 In Vitro Fertilization Laboratory 3 Center for Gerontology and Health Care Research, Women and Infants Hospital, Brown Medical School, Providence, RI and 4 Department of Obstetrics and Gynecology, University of South Florida, FL, USA

5 To whom correspondence should be addressed at: Department of Obstetrics and Gynecology, Fletcher Allen Health Care, University of Vermont, 111 Colchester Ave, Burlington, VT 05401, USA. E-mail: Kristen.Wright{at}vtmednet.org

BACKGROUND: Cigarette smoking is widely believed to be associated with decreased fecundity in naturally conceiving populations; however, the effect of female smoking on pregnancy outcomes in patients undergoing IVF is unclear. METHODS: A retrospective analysis of 389 consecutive patients undergoing first cycle IVF was performed. Outcomes of peak estradiol (E2) levels, log mean ovarian volume, number of oocytes retrieved, oocyte maturity in ICSI, fertilization rate, cleavage rate, embryo quality, percentage of high-quality embryos, pregnancy and live birth were assessed in patients reported as never smokers, past smokers and current smokers. Potential confounding variables evaluated included day 3 FSH, number of oocytes retrieved, embryo quality, caffeine and alcohol consumption. The population was also stratified by female age (<35 and ≥35 years). RESULTS: A total of 9.3% of our patients reported current smoking and 12.1% reported a history of smoking. Smoking status did not significantly affect pregnancy outcome, live birth rate or any other indicated outcome. CONCLUSIONS: A total of 21.4% of IVF patients in this study had past or present exposure to cigarette smoking with no measurable effect on IVF outcome.

Key words: cigarette smoking/infertility/IVF


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
A.L. Waylen, M. Metwally, G.L. Jones, A.J. Wilkinson, and W.L. Ledger
Effects of cigarette smoking upon clinical outcomes of assisted reproduction: a meta-analysis
Hum. Reprod. Update, January 1, 2009; 15(1): 31 - 44.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.