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Hum. Reprod. Advance Access originally published online on November 28, 2006
Human Reproduction 2007 22(2):323-336; doi:10.1093/humrep/del402
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ESHRE PGD Consortium data collection VI: cycles from January to December 2003 with pregnancy follow-up to October 2004

K.D. Sermon1,11, A. Michiels2, G. Harton3, C. Moutou4, S. Repping5, P.N. Scriven6, S. SenGupta7, J. Traeger-Synodinos8, K. Vesela9, S. Viville4, L. Wilton10 and J.C. Harper7

1 Centre for Medical Genetics 2 Centre for Reproductive Medicine, University Hospital and Medical School of the Dutch-speaking Brussels Free University (Vrije Universiteit Brussel, VUB), Brussels, Belgium 3 Genetics and IVF Institute, Fairfax, VA, USA 4 Service de la Biologie de la Reproduction, SIHCUS-CMCO, Schiltigheim, France 5 Center for Reproductive Medicine, Academic Medical Center, Fertility Laboratory, Amsterdam, The Netherlands 6 Department of Cytogenetics and Center for Preimplantation Genetic Diagnosis, Guy’s and St. Thomas’ NHS Foundation Trust, Guy’s Hospital 7 UCL Centre for PGD, Department of Obstetrics and Gynecology, University College London, London, UK 8 Laboratory of Medical Genetics, University of Athens, St. Sophia’s Children’s Hospital, Athens, Greece 9 Sanatorium Repromeda, Brno, Czech Republic and 10 Melbourne IVF, East Melbourne VIC, Australia

11 To whom correspondence should be addressed at: Centre for Medical Genetics, University Hospital and Medical School of the Dutch-speaking Brussels Free University (Vrije Universiteit Brussel, VUB), Laarbeeklaan 101, 1090 Brussels, Belgium. E-mail: karen.sermon{at}az.vub.ac.be

The sixth report of the ESHRE PGD Consortium is presented, relating to cycles collected for the calendar year 2003 and follow-up of the pregnancies and babies born up to October 2004. Since the beginning of the data collections, there has been a steady rise in the number of cycles, pregnancies and babies reported. For this report, 50 centres participated, reporting on 2984 cycles, 501 pregnancies and 373 babies born. Five hundred and twenty-nine cycles were reported for chromosomal abnormalities, 516 cycles were reported for monogenic diseases, 137 cycles were reported for sexing for X-linked diseases, 1722 cycles were reported for preimplantation genetic screening (PGS) and 80 cycles were reported for social sexing. Data VI is compared to the cumulative data for data collections I–V.

Key words: PGD/preimplantation genetic screening/fluorescence in-situ hybridization/PCR/ESHRE PGD Consortium


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