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Hum. Reprod. Advance Access originally published online on November 1, 2006
Human Reproduction 2007 22(3):629-634; doi:10.1093/humrep/del431
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

NEW DEBATE

Oocyte donation for stem cell research

H. Mertes1 and G. Pennings

Centre for Environmental Philosophy and Bioethics, Ghent University, Ghent, Belgium

1 To whom correspondence should be addressed at: Centre for Environmental Philosophy and Bioethics, Ghent University, Blandijnberg 2, B-9000 Ghent, Belgium. E-mail: heidi.mertes{at}ugent.be

The future success of stem cell research by means of somatic cell nuclear transfer (SCNT) depends on a sufficient supply of human oocytes. However, oocyte donation presents certain risks for the donor, and concerns for women’s welfare are rightly vocalized. At the same time, these risks are comparable with the risks faced by other healthy research subjects. Thus, research donation can withstand ethical scrutiny if it fulfils the same conditions as other research involving healthy human subjects. Specifically, this means that the benefits of the research project need to outweigh the harms, that risks must be minimized, that informed consent has to be guaranteed by averting undue inducement and the recruitment of vulnerable women and that donors can and should be reimbursed for their research participation.

Key words: ethics/oocyte donation/research subject/stem cell research/undue inducement


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A.L. Bredenoord, G. Pennings, and G. de Wert
Ooplasmic and nuclear transfer to prevent mitochondrial DNA disorders: conceptual and normative issues
Hum. Reprod. Update, November 1, 2008; 14(6): 669 - 678.
[Abstract] [Full Text] [PDF]



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