Skip Navigation


Hum. Reprod. Advance Access originally published online on October 27, 2006
Human Reproduction 2007 22(3):766-771; doi:10.1093/humrep/del421
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
22/3/766    most recent
del421v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by La Marca, A.
Right arrow Articles by Volpe, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by La Marca, A.
Right arrow Articles by Volpe, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Anti-Müllerian hormone measurement on any day of the menstrual cycle strongly predicts ovarian response in assisted reproductive technology

A. La Marca1, S. Giulini, A. Tirelli, E. Bertucci, T. Marsella, S. Xella and A. Volpe

Mother-Infant Department, Institute of Obstetrics and Gynecology, University of Modena and Reggio Emilia, Modena, Italy

1 To whom correspondence should be addressed at: Mother-Infant Department, Institute of Obstetrics and Gynecology, Policlinico di Modena, University of Modena and Reggio Emilia, Largo del Pozzo, 41100 Modena, Italy. E-mail: antlamarca{at}libero.it

BACKGROUND: Recently, a new marker, the anti-Müllerian hormone (AMH), has been evaluated as a marker of ovarian response. Serum AMH levels have been measured at frequent time-points during the menstrual cycle, suggesting the complete absence of fluctuation. The aim of this study was to evaluate whether serum AMH measurement on any day of the menstrual cycle could predict ovarian response in women undergoing assisted reproductive technology (ART). METHODS: This study included 48 women attending the IVF/ICSI programme. Blood withdrawal for AMH measurement was performed in all the patients independently of the day of the menstrual cycle. RESULTS: Women in the lowest AMH quartile (<0.4 ng/ml) were older and required a higher dose of recombinant FSH than women in the highest quartile (>7 ng/ml). All the cancelled cycles due to absent response were in the group of the lowest AMH quartile, whereas the cancelled cycles due to risk of ovarian hyperstimulation syndrome (OHSS) were in the group of the highest AMH quartile. This study demonstrated a strong correlation between serum AMH levels and ovarian response to gonadotrophin stimulation. CONCLUSION: For the first time, clinicians may have a reliable serum marker of ovarian response that can be measured independently of the day of the menstrual cycle.

Key words: AMH/IVF or ICSI/ovarian stimulation/poor response/OHSS

Submitted on August 1, 2006; resubmitted on September 25, 2006; accepted on September 29, 2006.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
K. Jayaprakasan, B.K. Campbell, J.F. Hopkisson, J.S. Clewes, I.R. Johnson, and N.J. Raine-Fenning
Effect of pituitary desensitization on the early growing follicular cohort estimated using anti-Mullerian hormone
Hum. Reprod., July 25, 2008; (2008) den282v1.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. van Disseldorp, M. J. Faddy, A. P. N. Themmen, F. H. de Jong, P. H. M. Peeters, Y. T. van der Schouw, and F. J. M. Broekmans
Relationship of Serum Antimullerian Hormone Concentration to Age at Menopause
J. Clin. Endocrinol. Metab., June 1, 2008; 93(6): 2129 - 2134.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
C. Gnoth, A.N. Schuring, K. Friol, J. Tigges, P. Mallmann, and E. Godehardt
Relevance of anti-Mullerian hormone measurement in a routine IVF program
Hum. Reprod., June 1, 2008; 23(6): 1359 - 1365.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
T.E.M. Verhagen, D.J. Hendriks, L.F.J.M.M. Bancsi, B.W.J. Mol, and F.J.M. Broekmans
The accuracy of multivariate models predicting ovarian reserve and pregnancy after in vitro fertilization: a meta-analysis
Hum. Reprod. Update, March 1, 2008; 14(2): 95 - 100.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
B.C.J.M. Fauser, K. Diedrich, P. Devroey, and on behalf of the Evian Annual Reproduction (EVAR)
Predictors of ovarian response: progress towards individualized treatment in ovulation induction and ovarian stimulation
Hum. Reprod. Update, January 1, 2008; 14(1): 1 - 14.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
T.-H. Lee, C.-H. Liu, C.-C. Huang, Y.-L. Wu, Y.-T. Shih, H.-N. Ho, Y.-S. Yang, and M.-S. Lee
Serum anti-mullerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles
Hum. Reprod., January 1, 2008; 23(1): 160 - 167.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.