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Hum. Reprod. Advance Access originally published online on November 9, 2006
Human Reproduction 2007 22(3):901; doi:10.1093/humrep/del437
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Letters to the editor

Reactive oxygen species and oocyte fertilization

F.F. Pasqualotto1,3 and E.B. Pasqualotto2

1 Institute of Biotechnology and 2 Center for Biological and Health Sciences, University of Caxias do Sul, RS, Brazil

3 To whom correspondence should be addressed at: Institute of Biotechnology, University of Caxias do Sul, RS, Brazil. E-mail: fabio.conception@terra.com.br/ fabio@conception-rs.com.br

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Sir,

The oocyte resides in a metabolically active environment consisting of steroid hormones, growth factors, cytokines, granulosa cells and leukocytes. Even though the impact of follicular fluid oxidative stress on oocyte maturation, fertilization and pregnancy is not clear, in bovine oocytes, the formation of reactive oxygen species (ROS) is reported to increase the developmental potential during in vitro maturation to . . . [Full Text of this Article]


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