Hum. Reprod. Advance Access originally published online on December 18, 2006
Human Reproduction 2007 22(4):1192; doi:10.1093/humrep/del469
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Letters to the editor |
Recombination in heterozygote inversion carriers
Unitat de Biologia Cel·lular, Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola del Vallès, Barcelona, Spain
1 To whom correspondence should be addressed at: Unitat de Biologia Cel·lular, Edifici C (Facultat de Ciències), Universitat Autònoma de Barcelona, 08193 Bellaterra, Cerdanyola del Vallès, Barcelona, Spain. E-mail: francesca.vidal@uab.es
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Sir,
We have read with interest the recent publication in Human Reproduction of Malan et al. (2006)
, a case report dealing with the evaluation of unbalanced sperm produced by a carrier of an inv(21)(p12q22.3).
In their work, the authors report a high amount of recombinant gametes (32.6%) from an inversion, which involves