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Hum. Reprod. Advance Access originally published online on June 21, 2007
Human Reproduction 2007 22(8):2345-2346; doi:10.1093/humrep/dem161
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© The Author 2007. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Letters to the Editor

Reply: Pregnancy is predictable: a large-scale prospective external validation of the prediction of spontaneous pregnancy in subfertile couples

Jan Willem van der Steeg1,2,4,8, Pieternel Steures1,2,4, Marinus J.C. Eijkemans1, J. Dik F. Habbema1, Peter G.A. Hompes4, Frank J. Broekmans5, Thierry H.J.H.M. van Dessel6, Patrick M.M. Bossuyt3, Fulco van der Veen2 and Ben W.J. Mol2,7

1 Department of Public Health, Erasmus MC, University of Medical Center, Rotterdam 2 Academic Medical Center, Center for Reproductive Medicine, Room H4-213, Department of Obstetrics and Gynaecology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands 3 Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, Amsterdam 4 Department of Obstetrics and Gynaecology, Vrije Universiteit Medical Center, Amsterdam 5 Division of Reproductive Medicine, Department of Perinatology and Gynaecology, University Medical Center, Utrecht 6 Department of Obstetrics and Gynaecology, TweeSteden Ziekenhuis, Tilburg 7 Department of Obstetrics and Gynaecology, Maxima Medical Center, Veldhoven, The Netherlands

8 Correspondence address. Tel: +31-20-5663857; Fax: +31-20-6963489; E-mail: j.w.vandersteeg@amc.uva.nl

The first 10% of the full text of this article appears below.

Sir,

We thank Drs Smeenk and colleagues for their interest in our work. The authors address several issues. First, they state that a prognostic model is only useful if it changes the prior probability for pregnancy in an accurate way, and suggest that the Hunault model does not change the prior probability of 32% that most couples would have for spontaneous conception within . . . [Full Text of this Article]


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