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Hum. Reprod. Advance Access originally published online on July 31, 2007
Human Reproduction 2007 22(9):2574-2575; doi:10.1093/humrep/dem229
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© The Author 2007. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Letters to the Editor

Reply: Testis development, beef consumption and study methods

Shanna H. Swan1,4, Fan Liu1, James.W. Overstreet2, Charlene Brazil2 and Niels Erik Skakkebaek3

1 Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14624, USA 2 ITEH, University of California, Davis, CA 95616, USA 3 University Department of Growth and Reproduction, Rigshospitalet, GR-5064, Blegdemsvej 9-2100, Copenhagen, Denmark

4 Correspondence address. Tel: +001 585 273 3521; Fax: +001 585 276 2171; E-mail: shanna_swan@urmc.rochester.edu

The first 10% of the full text of this article appears below.

Sir,

We appreciate the thoughtful letter by Drs. Amann and Seidel regarding our paper (Swan et al., 2007Go) in which they correctly describe the goal of the study and their agreement with the importance we attribute to it. They did have several reservations, however, which we will try to address.

The first of these is a concern that the volume of the semen sample and total sperm count were not discussed. We chose not to analyse sample volume in relation to mother's beef because this parameter has seldom if ever been associated with exogenous exposures in prior studies, including ours (Swan et al., 2003Go). However, in response to this letter we did so (Ejaculate volume was estimated by specimen weight, assuming a semen density of 1.0 g/ml). For mothers reporting ≤7 beef meals/week, the . . . [Full Text of this Article]


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