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Hum. Reprod. Advance Access originally published online on January 31, 2008
Human Reproduction 2008 23(4):741-755; doi:10.1093/humrep/dem354
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© The Author 2008. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ESHRE PGD consortium data collection VII: cycles from January to December 2004 with pregnancy follow-up to October 2005

J.C. Harper1,11, C. de Die-Smulders2, V. Goossens3, G. Harton4, C. Moutou5, S. Repping6, P.N Scriven7, S. SenGupta1, J. Traeger-Synodinos8, M.C. Van Rij2, S. Viville5, L. Wilton9 and K.D. Sermon10

1 UCL Centre for PGD, Institute for Women's Health, University College London, 86-96 Chenies Mews, WC1E6HX London, UK 2 PGD Working Group Maastricht, Department of Clinical Genetics, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands 3 ESHRE Central Office, Meerstraat 60, 1852 Grimbergen, Belgium 4 Genetics and IVF Institute, 3015 Williams Drive, Fairfax, VA 22031, USA 5 Service de la Biologie de la Reproduction, SIHCUS-CMCO, 19, Rue Louis Pasteur, BP120, 67303 Schiltigheim, France 6 Center for Reproductive Medicine, Academic Medical Center, Fertility Laboratory (A1-229), Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands 7 Department of Cytogenetics and Center for Preimplantation Genetic Diagnosis, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, St Thomas Street, London SE1 9RT, UK 8 Laboratory of Medical Genetics, University of Athens, St Sophia's Children's Hospital, 11527 Athens, Greece 9 Melbourne IVF, 320 Victoria Parade, 3002 East Melbourne, VIC, Australia 10 Department of Embryology and Genetics of the VUB and Centre for Medical Genetics of the Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium

11 Correspondence address. Tel: +44-20-7679-6072; E-mail: joyce.harper{at}ucl.ac.uk

The seventh report of the ESHRE PGD Consortium is presented documenting cycles collected for the calendar year 2004 and follow-up of the pregnancies and babies born subsequent to these cycles up to October 2005. Since the beginning of the data collections, there has been a steady increase in the number of cycles, pregnancies and babies reported. For data collection VII, 45 centres have participated, reporting on 3358 cycles to oocyte retrieval (OR), 679 pregnancies and 528 babies born. Five hundred and fifty nine OR were reported for chromosomal abnormalities, 113 OR for sexing for X-linked diseases, 520 OR for monogenic diseases, 2087 OR for PGS, and 79 OR for social sexing. Data VII is compared with the cumulative data for data collections I–VI.

Key words: preimplantation genetic diagnosis/preimplantation genetic screening/fluorescence in situ hybridization/polymerase chain reaction/ESHRE PGD Consortium

Submitted on August 22, 2007; resubmitted on August 22, 2007; accepted on October 9, 2007.


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