Skip Navigation

This Article
Right arrow Full Text (PDF )
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (100)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Piette, C.
Right arrow Articles by Spira, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Piette, C.
Right arrow Articles by Spira, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Human Reproduction, Vol. 5, No. 1, pp. 56-59, 1990
© 1990 European Society of Human Reproduction and Embryology

research-article

In-vitro fertilization: influence of women's age on pregnancy rates

C. Piette, J. de Mouzon, A. Bachelot and A. Spira

Hôpital de Bicêtre 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre Cedex, France

An analysis of the influence of women's age on the results of in-vitro fertilization was performed, using 5590 attempts collected during the year 1986. Increasing age was found to be related to decreased success rates from 19.8% per attempt below the age of 25 years, to 9% per attempt at 40 years or more. A cut-off point was found between the ages of 36 and 37 years, using a mathematical model. The decrease was related to a reduction in oocyte production (4.3 ± 2.8 at 25 years or less and 3.3 ± 2.1 at 40 years or more, P > 0.001), and to a reduced implantation rate, whatever the number of transferred embryos. These findings were not due to spouse's age, rank of attempt, infertility diagnosis or oocyte stimulation regimen, since the effect of age remained significant when a logistical model including these confounders was applied. Finally, a woman's age must be considered as a prognostic factor when IVF is proposed to infertile couples.

Key words: age/epidemiology/TVF/pregnancy rate


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
T. Hardarson, C. Hanson, K. Lundin, T. Hillensjo, L. Nilsson, J. Stevic, E. Reismer, K. Borg, M. Wikland, and C. Bergh
Preimplantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate: a randomized controlled trial
Hum. Reprod., December 1, 2008; 23(12): 2806 - 2812.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
N. S. Macklon, R. L. Stouffer, L. C. Giudice, and B. C. J. M. Fauser
The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization
Endocr. Rev., April 1, 2006; 27(2): 170 - 207.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. X. Wang
Life table (survival) analysis to generate cumulative pregnancy rates in assisted reproduction: an alternative method of calculating the cumulative pregnancy rate in assisted reproduction technology
Hum. Reprod., January 1, 2006; 21(1): 1 - 2.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. Tesarik, A. Hazout, and C. Mendoza
Improvement of delivery and live birth rates after ICSI in women aged >40 years by ovarian co-stimulation with growth hormone
Hum. Reprod., September 1, 2005; 20(9): 2536 - 2541.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
B. Kuhnert and E. Nieschlag
Reproductive functions of the ageing male
Hum. Reprod. Update, July 1, 2004; 10(4): 327 - 339.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
R. D. Schramm, A. M. Paprocki, and B. D. Bavister
Features associated with reproductive ageing in female rhesus monkeys
Hum. Reprod., June 1, 2002; 17(6): 1597 - 1603.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. Balasch
Investigation of the infertile couple: Investigation of the infertile couple in the era of assisted reproductive technology: a time for reappraisal
Hum. Reprod., November 1, 2000; 15(11): 2251 - 2257.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M. Creus, J. Penarrubia, F. Fabregues, E. Vidal, F. Carmona, R. Casamitjana, J. A. Vanrell, and J. Balasch
Day 3 serum inhibin B and FSH and age as predictors of assisted reproduction treatment outcome
Hum. Reprod., November 1, 2000; 15(11): 2341 - 2346.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
Y. Menezo and Y. Barak
Comparison between day-2 embryos obtained either from ICSI or resulting from short insemination IVF: influence of maternal age
Hum. Reprod., August 1, 2000; 15(8): 1776 - 1780.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
C. Battaglia, M. Salvatori, N. Maxia, F. Petraglia, F. Facchinetti, and A. Volpe
Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients
Hum. Reprod., July 1, 1999; 14(7): 1690 - 1697.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
F. Devreker, S. Emiliani, P. Revelard, M. Van den Bergh, I. Govaerts, and Y. Englert
Comparison of two elective transfer policies of two embryos to reduce multiple pregnancies without impairing pregnancy rates
Hum. Reprod., January 1, 1999; 14(1): 83 - 89.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.