Human Reproduction, Vol. 8, No. 1, pp. 127-129, 1993
© 1993 European Society of Human Reproduction and Embryology
case-report |
CASE REPORT: A monozygotic twin pregnancy after application of zona rubbing on a frozenthawed blastocyst
IVF Centre, Van Helmont Ziekenhuis Vaartstraat 42, B 1800 Vilvoorde, Belgium
Correspondence: 1To whom correspondence should be addressed
Assisted hatching techniques enhance the success rate of implantation of in-vitro fertilized human embryos. We report here the successful transfer of a frozenthawed human blastocyst on which we applied a non-invasive zona rubbing technique (reduction of the thickness of the zona pellucida by gentle rubbing with a microneedle). The implantation in the uterus led to the delivery of healthy monozygotic twins.
Key words: assisted hatching/cryopreservation/human blastocyst/in-vitro fertilization/zona rubbing
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