Human Reproduction, Vol. 8, No. 7, pp. 1055-1060, 1993
© 1993 European Society of Human Reproduction and Embryology
other |
Higher success rate by intracytoplasmic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles
Centre for Reproductive Medicine, Academisch Ziekenhuis VUB Laarbeeklaan 101, B-1090 Brussels, Belgium 2Biostatistics Department, Academisch Ziekenhuis VUB Laarbeeklaan 101, B-1090 Brussels, Belgium 3Centre for Medical Genetics, Academisch Ziekenhuis VUB Laarbeeklaan 101, B-1090 Brussels, Belgium
Correspondence: 1To whom correspondence should be addressed
Subzonal insemination (SUZI) and intracytoplasmic sperm injection (ICSI) were carried out in 300 treatment cycles in couples unable to be helped by coventional in-vitro fertilization treatment. More oocytes were damaged by ICSI (13.5%) than by SUZI (7.1%). The normal fertilization rate was substantially higher after ICSI (51.0%) than after SUZI (14.3%) and was related to the semen characteristics. The cleavage rate was similar for both procedures (77%). After 217 embryo transfers (72.3% of the treatment cycles) 66 pregnancies were established, i.e. pregnancy rates of 22.0% per started cycle and 30.4% per embryo transfer. So far, pregnancy loss has occurred in 27.3% of the pregnancies, nine healthy children have been born after eight deliveries and 41 clinical pregnancies are progressing uneventfully. Chorionic villus sampling or amniocentesis have been performed in 35 pregnancies and 39 normal fetal karyotypes have been obtained after cytogenetic analysis.
Key words: intracytoplasmic spermatozoon injection/male-factor infertility/oocyte/spermatozoon/subzonal insemination
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  S. E M Lewis Is sperm evaluation useful in predicting human fertility? Reproduction, July 1, 2007; 134(1): 31 - 40. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ghetler, S. Yavin, R. Shalgi, and A. Arav The effect of chilling on membrane lipid phase transition in human oocytes and zygotes Hum. Reprod., December 1, 2005; 20(12): 3385 - 3389. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.R. Brison, F.D. Houghton, D. Falconer, S.A. Roberts, J. Hawkhead, P.G. Humpherson, B.A. Lieberman, and H.J. Leese Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover Hum. Reprod., October 1, 2004; 19(10): 2319 - 2324. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Poppe, D. Glinoer, H. Tournaye, J. Schiettecatte, P. Devroey, A. van Steirteghem, P. Haentjens, and B. Velkeniers Impact of Ovarian Hyperstimulation on Thyroid Function in Women with and without Thyroid Autoimmunity J. Clin. Endocrinol. Metab., August 1, 2004; 89(8): 3808 - 3812. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. de Kretser Is Spermatogenic Damage Associated with Leydig Cell Dysfunction? J. Clin. Endocrinol. Metab., July 1, 2004; 89(7): 3158 - 3160. [Full Text] [PDF]
|
|
|
|
 |
|
 P. Devroey and A. Van Steirteghem A review of ten years experience of ICSI Hum. Reprod. Update, January 1, 2004; 10(1): 19 - 28. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Shiloh, S.L. Baratz, M. Koifman, D. Ishai, D. Bidder, Z. Weiner-Meganzi, and M. Dirnfeld The impact of cigarette smoking on zona pellucida thickness of oocytes and embryos prior to transfer into the uterine cavity Hum. Reprod., January 1, 2004; 19(1): 157 - 159. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Tesarik Associate Editor's commentary: Rescue ICSI revisited Hum. Reprod., October 1, 2003; 18(10): 2122 - 2123. [Full Text] [PDF]
|
|
|
|
|
|
K. Poppe, D. Glinoer, H. Tournaye, P. Devroey, A. van Steirteghem, L. Kaufman, and B. Velkeniers Assisted Reproduction and Thyroid Autoimmunity: An Unfortunate Combination? J. Clin. Endocrinol. Metab., September 1, 2003; 88(9): 4149 - 4152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Osmanagaoglu, V. Vernaeve, E. Kolibianakis, H. Tournaye, M. Camus, A. Van Steirteghem, and P. Devroey Cumulative delivery rates after ICSI treatment cycles with freshly retrieved testicular sperm: a 7-year follow-up study Hum. Reprod., September 1, 2003; 18(9): 1836 - 1840. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Bonduelle, E. Van Assche, H. Joris, K. Keymolen, P. Devroey, A. Van Steirteghem, and I. Liebaers Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters Hum. Reprod., October 1, 2002; 17(10): 2600 - 2614. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Hawes, C. Sapienza, and K. E. Latham Ooplasmic donation in humans: The potential for epigenic modifications Hum. Reprod., April 1, 2002; 17(4): 850 - 852. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I.D. Morris, S. Ilott, L. Dixon, and D.R. Brison The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development Hum. Reprod., April 1, 2002; 17(4): 990 - 998. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Bonduelle, I. Liebaers, V. Deketelaere, M.-P. Derde, M. Camus, P. Devroey, and A. Van Steirteghem Neonatal data on a cohort of 2889 infants born after ICSI (1991-1999) and of 2995 infants born after IVF (1983-1999) Hum. Reprod., March 1, 2002; 17(3): 671 - 694. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Lahav-Baratz, E. Rothschild, B. Grach, M. Koifman, H. Shiloh, D. Ishai, and M. Dirnfeld The value of sperm pooling and cryopreservation in patients with transient azoospermia or severe oligoasthenoteratozoospermia Hum. Reprod., January 1, 2002; 17(1): 157 - 160. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Meriano, J. Alexis, S. Visram-Zaver, M. Cruz, and R. F. Casper Tracking of oocyte dysmorphisms for ICSI patients may prove relevant to the outcome in subsequent patient cycles Hum. Reprod., October 1, 2001; 16(10): 2118 - 2123. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Johnson, C. Staub, W. B. Neaves, and R. Yanagimachi Live human germ cells in the context of their spermatogenic stages Hum. Reprod., August 1, 2001; 16(8): 1575 - 1582. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.T. Langley, D.M. Marek, D.K. Gardner, K.M. Doody, and K.J. Doody Extended embryo culture in human assisted reproduction treatments Hum. Reprod., May 1, 2001; 16(5): 902 - 908. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Gekas, F. Thepot, C. Turleau, J.P. Siffroi, J.P. Dadoune, S. Briault, M. Rio, G. Bourouillou, F. Carre-Pigeon, R. Wasels, et al. Chromosomal factors of infertility in candidate couples for ICSI: an equal risk of constitutional aberrations in women and men Hum. Reprod., January 1, 2001; 16(1): 82 - 90. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Horne, A. Atkinson, D.R. Brison, J. Radford, J.A.L. Yin, E.C.O. Edi-Osagie, E.H.E. Pease, and B.A. Lieberman Achieving pregnancy against the odds: successful implantation of frozen-thawed embryos generated by ICSI using spermatozoa banked prior to chemo/radiotherapy for Hodgkin's disease and acute leukaemia: Case Report Hum. Reprod., January 1, 2001; 16(1): 107 - 109. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Akutsu, L. L. Tres, H. Tateno, R. Yanagimachi, and A. L. Kierszenbaum Offspring from Normal Mouse Oocytes Injected with Sperm Heads from the azh/azh Mouse Display More Severe Sperm Tail Abnormalities than the Original Mutant Biol Reprod, January 1, 2001; 64(1): 249 - 256. [Abstract] [Full Text]
|
|
|
|
|
|
I. De Croo, J. Van der Elst, K. Everaert, P. De Sutter, and M. Dhont Fertilization, pregnancy and embryo implantation rates after ICSI in cases of obstructive and non-obstructive azoospermia Hum. Reprod., June 1, 2000; 15(6): 1383 - 1388. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.E. Felberbaum, C. Albano, M. Ludwig, H. Riethmuller-Winzen, M. Grigat, P. Devroey, and K. Diedrich Ovarian stimulation for assisted reproduction with HMG and concomitant midcycle administration of the GnRH antagonist Cetrorelix according to the multiple dose protocol: a prospective uncontrolled phase III study Hum. Reprod., May 1, 2000; 15(5): 1015 - 1020. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Frydman, C.M. Howles, and F. Truong A double-blind, randomized study to compare recombinant human follicle stimulating hormone (FSH; Gonal-F(R)) with highly purified urinary FSH (Metrodin(R) HP) in women undergoing assisted reproductive techniques including intracytoplasmic sperm injection Hum. Reprod., March 1, 2000; 15(3): 520 - 525. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Vegetti, E. Van Assche, A. Frias, G. Verheyen, M. M. Bianchi, M. Bonduelle, I. Liebaers, and A. Van Steirteghem Correlation between semen parameters and sperm aneuploidy rates investigated by fluorescence in-situ hybridization in infertile men Hum. Reprod., February 1, 2000; 15(2): 351 - 365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L.A.J. Van der Westerlaken, F.M. Helmerhorst, J. Hermans, and N. Naaktgeboren Intracytoplasmic sperm injection: position of the polar body affects pregnancy rate Hum. Reprod., October 1, 1999; 14(10): 2565 - 2569. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Gerris, D. De Neubourg, K. Mangelschots, E. Van Royen, M. Van de Meerssche, and M. Valkenburg Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: a prospective randomized clinical trial Hum. Reprod., October 1, 1999; 14(10): 2581 - 2587. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Osmanagaoglu, H. Tournaye, M. Camus, M. Vandervorst, A. Van Steirteghem, and P. Devroey Cumulative delivery rates after intracytoplasmic sperm injection: 5 year follow-up of 498 patients Hum. Reprod., October 1, 1999; 14(10): 2651 - 2655. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.G. Pang, S.F. Hoegerman, A.J. Cuticchia, S.Y. Moon, G.F. Doncel, A.A. Acosta, and W.G. Kearns Detection of aneuploidy for chromosomes 4, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 21, X and Y by fluorescence in-situ hybridization in spermatozoa from nine patients with oligoasthenoteratozoospermia undergoing intracytoplasmic sperm injection Hum. Reprod., May 1, 1999; 14(5): 1266 - 1273. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. D. Palermo, P. N. Schlegel, J. J. Hariprashad, B. Ergun, A. Mielnik, N. Zaninovic, L. L. Veeck, and Z. Rosenwaks Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men Hum. Reprod., March 1, 1999; 14(3): 741 - 748. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.M. Vendrell, F. Garcia, A. Veiga, G. Calderon, S. Egozcue, J. Egozcue, and P.N. Barri Meiotic abnormalities and spermatogenic parameters in severe oligoasthenozoospermia Hum. Reprod., February 1, 1999; 14(2): 375 - 378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G.-J. Rho,, S. Kawarsky,, W. H. Johnson,, K. Kochhar,, and K. J. Betteridge Sperm and Oocyte Treatments to Improve the Formation of Male and Female Pronuclei and Subsequent Development Following Intracytoplasmic Sperm Injection into Bovine Oocytes Biol Reprod, October 1, 1998; 59(4): 918 - 924. [Abstract] [Full Text]
|
|
|
|
|
|
P. N. Schlegel and S. K. Girardi In Vitro Fertilization for Male Factor Infertility J. Clin. Endocrinol. Metab., March 1, 1997; 82(3): 709 - 716. [Full Text] [PDF]
|
|
|
|
 |
|
 Y Kimura and R Yanagimachi Mouse oocytes injected with testicular spermatozoa or round spermatids can develop into normal offspring Development, January 8, 1995; 121(8): 2397 - 2405. [Abstract] [PDF]
|
|