Skip Navigation



Hum. Reprod. Advance Access published online on April 22, 2004

Human Reproduction, doi:10.1093/humrep/deh226
© 2004 by European Society of Human Reproduction and Embryology
This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
19/6/1472    most recent
deh226v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Attar, E.
Right arrow Articles by Chambers, J. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Attar, E.
Right arrow Articles by Chambers, J. T.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Received January 5, 2004
Accepted January 28, 2004

Article

Evolutive peritoneal disease after conservative management and the use of infertility drugs in a patient with stage IIIC borderline micro-papillary serous carcinoma (MPSC) of the ovary: Case report

Erkut Attar 1*, Sinan Berkman 2, Samet Topuz 2, Bulent Baysal 1, Suleyman Akhan 2, Joseph T. Chambers 3

1 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Istanbul University, School of Medicine, 34093 Istanbul, Turkey
2 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Istanbul University, School of Medicine, 34093 Istanbul, Turkey
3 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, St. Luke’s-Roosevelt Hospital Center, New York, NY 10019, USA

* To whom correspondence should be addressed. E-mail: attar{at}superonline.com.


   Abstract

A young nulliparous woman with stage IIIC bilateral borderline micro-papillary serous carcinoma (MPSC) of the ovary underwent conservative surgery with optimal preservation of future fertility. The left ovary and a substantial portion of the right ovary were removed. The patient became pregnant at the first IVF cycle attempted after conservative management. A Cesarean section was performed in the 37th week of pregnancy and combined with very precise exploration; there were multiple non-invasive implants on the peritoneal surface and liver, and contra-lateral ovarian tissue was of normal appearance. Abdominal hysterectomy and right oophorectomy were done as a definitive treatment 3 months after the Caesarean section. The patient showed a rapid progression to invasive ovarian carcinoma in this period of time. MPSC has the greatest risk of malignant transformation among the advanced stage serous borderline tumours. Fertility-sparing surgery is an option for young, childless women who would like to preserve their fertility. However, the treatment must be taken very cautiously and requires rigorous surveillance.

Key words: Key words: borderline ovarian tumour/conservative surgery/fertility


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
Ann OncolHome page
C. Uzan, A. Kane, A. Rey, S. Gouy, P. Duvillard, and P. Morice
Outcomes after conservative treatment of advanced-stage serous borderline tumors of the ovary
Ann. Onc., July 16, 2009; (2009) mdp267v1.
[Abstract] [Full Text] [PDF]


Home page
Hum ReprodHome page
C. Basille, F. Olivennes, J. Le Calvez, N. Beron-Gaillard, G. Meduri, C. Lhomme, P. Duvillard, J. Benard, and P. Morice
Impact of gonadotrophins and steroid hormones on tumour cells derived from borderline ovarian tumours
Hum. Reprod., December 1, 2006; 21(12): 3241 - 3245.
[Abstract] [Full Text] [PDF]



Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.