Hum. Reprod. Advance Access published online on April 22, 2004
Human Reproduction, doi:10.1093/humrep/deh226
© 2004 by European Society of Human Reproduction and Embryology
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1 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Istanbul University, School of Medicine, 34093 Istanbul, Turkey
* To whom correspondence should be addressed. E-mail: attar{at}superonline.com.
A young nulliparous woman with stage IIIC bilateral borderline micro-papillary serous carcinoma (MPSC) of the ovary underwent conservative surgery with optimal preservation of future fertility. The left ovary and a substantial portion of the right ovary were removed. The patient became pregnant at the first IVF cycle attempted after conservative management. A Cesarean section was performed in the 37th week of pregnancy and combined with very precise exploration; there were multiple non-invasive implants on the peritoneal surface and liver, and contra-lateral ovarian tissue was of normal appearance. Abdominal hysterectomy and right oophorectomy were done as a definitive treatment 3 months after the Caesarean section. The patient showed a rapid progression to invasive ovarian carcinoma in this period of time. MPSC has the greatest risk of malignant transformation among the advanced stage serous borderline tumours. Fertility-sparing surgery is an option for young, childless women who would like to preserve their fertility. However, the treatment must be taken very cautiously and requires rigorous surveillance. Key words:
Key words: borderline ovarian tumour/conservative surgery/fertility
Accepted January 28, 2004
Article
Evolutive peritoneal disease after conservative management and the use of infertility drugs in a patient with stage IIIC borderline micro-papillary serous carcinoma (MPSC) of the ovary: Case report
2 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Istanbul University, School of Medicine, 34093 Istanbul, Turkey
3 Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, St. Luke’s-Roosevelt Hospital Center, New York, NY 10019, USA
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