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Hum. Reprod. Advance Access published online on June 30, 2004
Human Reproduction, doi:10.1093/humrep/deh/393
© 2004 by European Society of Human Reproduction and Embryology
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Received February 19, 2004
Accepted June 3, 2004

Case Report

Ejaculation failure on the day of oocyte retrieval for IVF: Case report

M. Emery 1*, A. Senn 2, M. Wisard 3, M. Germond 1

1 Reproductive Medicine Unit (RMU), Department of Obstetrics and Gynaecology, Centre Hospitalier Universitaire Vaudois (CHUV), 1011 Lausanne, Switzerland
2 Laboratory of Andrology associated with the RMU, 1001 Lausanne, Switzerland
3 Urology Department, CHUV, 1011 Lausanne, Switzerland

* To whom correspondence should be addressed. E-mail: marysa.emery{at}chuv.hospvd.ch.


  Abstract

Unexpected ejaculation failure on the day of oocyte retrieval for IVF occurs once or twice a year in our Reproductive Medicine Unit, where ~500 oocyte retrievals are performed each year. Two clinical situations which occurred in 2001 are presented. In the first case, sperm were finally obtained by epididymal aspiration and resulted in the fertilization of five oocytes by ICSI. The transfer of two fresh embryos did not result in a pregnancy and the three supernumerary zygotes were cryopreserved. The male patient presented an anxio-depressive episode necessitating psychiatric hospitalization 1 week after the oocyte retrieval. In the second case, no sperm were obtained and the four oocytes were therefore lost. The couple went through a crisis in their relationship and tried another cycle of IVF 10 months later, after the preventive cryopreservation of a sperm sample. On the day of oocyte retrieval the patient was unable to produce a fresh sample but three zygotes were obtained through ICSI using the back-up cryopreserved sperm. Two embryos were transferred but no pregnancy ensued. The clinical decision-making processes for these two cases are described, as well as the measures employed to help prevent these unfortunate situations.

Keywords: anejaculation; counselling; ejaculation failure; IVF; oocyte retrieval.
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