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Hum. Reprod. Advance Access published online on July 8, 2004
Human Reproduction, doi:10.1093/humrep/deh414
© 2004 by European Society of Human Reproduction and Embryology
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Received February 9, 2004
Revised March 19, 2004
Accepted June 22, 2004

Article

Prevalence of depressive and anxiety disorders in an assisted reproductive technique clinic

Ting-Hsiu Chen 1, Sheng-Ping Chang 2, Chia-Fen Tsai 1, Kai-Dih Juang 3*

1 Department of Psychiatry, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan
2 Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan
3 Department of Psychiatry, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Psychiatry, Tri-Service, Geneva Hospital, Taipei, Taiwan

* To whom correspondence should be addressed. E-mail: kd.juang{at}msa.hinet.net.


  Abstract

BACKGROUND: Little is known about the prevalence of specific depressive and anxiety disorders in women before a new course of assisted reproductive technology treatment. Few studies have adopted the proper psychiatric diagnostic procedures. METHODS: All consecutive women visiting the assisted reproduction clinic of a university-affiliated medical centre, with the intention of starting a new assisted reproduction treatment course, were recruited. A psychiatrist made a diagnosis of psychiatric disorders using a structured interview, the Mini-International Neuropsychiatric Interview (MINI). RESULTS: Of a total of 112 participants, 40.2% had a psychiatric disorder. The most common diagnosis was generalized anxiety disorder (23.2%), followed by major depressive disorder (17.0%), and dysthymic disorder (9.8%). Participants with a psychiatric morbidity did not differ from those without in terms of age, education, income, or years of infertility. Women with a history of previous assisted reproduction treatment did not differ from those without in depression or anxiety. CONCLUSIONS: Depressive and anxiety disorders were highly prevalent among women who visited an assisted reproduction clinic for a new course of the treatment. Demographic features and a history of previous assisted reproduction treatment were not risk factors for these psychiatric morbidities in the assisted reproduction clinic.

Keywords: assisted reproductive technology; depression; Hospital Anxiety and Depression Scale (HADS); mental disorder; Mini-International Neuropsychiatric Interview (MINI).
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