Skip Navigation



Hum. Reprod. Advance Access published online on August 19, 2004
Human Reproduction, doi:10.1093/humrep/deh485
© 2004 by European Society of Human Reproduction and Embryology
This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
19/11/2523    most recent
deh485v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Fedorcsák, P.
Right arrow Articles by Tanbo, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fedorcsák, P.
Right arrow Articles by Tanbo, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Received October 20, 2003
Revised May 27, 2004
Accepted July 26, 2004

Article

Impact of overweight and underweight on assisted reproduction treatment

Péter Fedorcsák 1*, Per Olav Dale 1, Ritsa Storeng 1, Gudvor Ertzeid 1, Sverre Bjercke 1, Nan Oldereid 1, Anne K. Omland 1, Thomas Åbyholm 1, Tom Tanbo 1

1 Department of Obstetrics and Gynaecology, Rikshospitalet University Hospital, Oslo, Norway

* To whom correspondence should be addressed. E-mail: peter.fedorcsak{at}klinmed.uio.no.


  Abstract

BACKGROUND: Underweight and overweight may affect reproduction and interfere with treatment of infertility. The purpose of this report is to describe the independent effect of body weight on treatment with IVF and ICSI. METHODS: Records of 5019 IVF or ICSI treatments in 2660 couples were reviewed. The influence of body mass index (BMI) on treatment outcome was examined, after accounting for differences in age and infertility diagnosis. RESULTS: The cumulative live birth rate within three treatment cycles was 41.4% [95% confidence interval (CI) 32.1-50.7] in obese women with BMI ≥30 kg/m2 and 50.3 (95% CI 47.0-53.7) in normal weight women with BMI 18.5-24.9 kg/m2. Obesity was associated with an increased risk of early pregnancy loss occurring before 6 weeks gestation. Positive correlation between BMI and gonadotrophin requirement during stimulation and negative correlation between BMI and number of collected oocytes were observed. Underweight (BMI <18.5 kg/m2) was not related to an impaired outcome of IVF or ICSI. CONCLUSIONS: Obesity is associated with lower chances for live birth after IVF and ICSI and with an impaired response to ovarian stimulation.

Keywords: body mass index; insulin resistance; IVF; PCOS.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
D. A. Van Vugt
Brain imaging studies of appetite in the context of obesity and the menstrual cycle
Hum. Reprod. Update, November 19, 2009; (2009) dmp051v1.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
A. La Marca, G. Sighinolfi, D. Radi, C. Argento, E. Baraldi, A. C. Artenisio, G. Stabile, and A. Volpe
Anti-Mullerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART)
Hum. Reprod. Update, September 30, 2009; (2009) dmp036v1.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. Devroey, M. Aboulghar, J. Garcia-Velasco, G. Griesinger, P. Humaidan, E. Kolibianakis, W. Ledger, C. Tomas, and B. C.J.M. Fauser
Improving the patient's experience of IVF/ICSI: a proposal for an ovarian stimulation protocol with GnRH antagonist co-treatment
Hum. Reprod., April 1, 2009; 24(4): 764 - 774.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. Maheshwari, G. Scotland, J. Bell, A. McTavish, M. Hamilton, and S. Bhattacharya
The direct health services costs of providing assisted reproduction services in overweight or obese women: a retrospective cross-sectional analysis
Hum. Reprod., March 1, 2009; 24(3): 633 - 639.
[Abstract] [Full Text] [PDF]

Home page
 British Journal of Diabetes & Vascular DiseaseHome page
S. M Nelson
Obesity, insulin resistance and assisted conception
The British Journal of Diabetes & Vascular Disease, January 1, 2009; 9(1): 23 - 26.
[Abstract] [PDF]

Home page
 Hum ReprodHome page
M. L. Sneed, M. L. Uhler, H. E. Grotjan, J. J. Rapisarda, K. J. Lederer, and A. N. Beltsos
Body mass index: impact on IVF success appears age-related
Hum. Reprod., August 1, 2008; 23(8): 1835 - 1839.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
C. E. Minge, B. D. Bennett, R. J. Norman, and R. L. Robker
Peroxisome Proliferator-Activated Receptor-{gamma} Agonist Rosiglitazone Reverses the Adverse Effects of Diet-Induced Obesity on Oocyte Quality
Endocrinology, May 1, 2008; 149(5): 2646 - 2656.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
Z. Veleva, A. Tiitinen, S. Vilska, C. Hyden-Granskog, C. Tomas, H. Martikainen, and J. S. Tapanainen
High and low BMI increase the risk of miscarriage after IVF/ICSI and FET
Hum. Reprod., April 1, 2008; 23(4): 878 - 884.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
A. Maheshwari, L. Stofberg, and S. Bhattacharya
Effect of overweight and obesity on assisted reproductive technology a systematic review
Hum. Reprod. Update, September 1, 2007; 13(5): 433 - 444.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M.F.G. Verberg, M.J.C. Eijkemans, N.S. Macklon, E.M.E.W. Heijnen, B.C.J.M. Fauser, and F.J. Broekmans
Predictors of low response to mild ovarian stimulation initiated on cycle day 5 for IVF
Hum. Reprod., July 1, 2007; 22(7): 1919 - 1924.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
G.F. Homan, M. Davies, and R. Norman
The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review
Hum. Reprod. Update, May 1, 2007; 13(3): 209 - 223.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. Fedorcsak, M. Raki, and R. Storeng
Characterization and depletion of leukocytes from cells isolated from the pre-ovulatory ovarian follicle
Hum. Reprod., April 1, 2007; 22(4): 989 - 994.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
G.H. Woldringh, M.H.A. Frunt, J.A.M. Kremer, and M.E.A. Spaanderman
Decreased ovarian reserve relates to pre-eclampsia in IVF/ICSI pregnancies
Hum. Reprod., November 1, 2006; 21(11): 2948 - 2954.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
G. G. Gosman, H. I. Katcher, and R. S. Legro
Obesity and the role of gut and adipose hormones in female reproduction
Hum. Reprod. Update, September 1, 2006; 12(5): 585 - 601.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
The ESHRE Capri Workshop Group
Nutrition and reproduction in women
Hum. Reprod. Update, May 1, 2006; 12(3): 193 - 207.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
V. Martinet, Y. Manigart, S. Rozenberg, B. Becker, M. Gerard, and A. Delvigne
Ovarian response to stimulation of HIV-positive patients during IVF treatment: a matched, controlled study
Hum. Reprod., May 1, 2006; 21(5): 1212 - 1217.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. Thurin, T. Hardarson, J. Hausken, B. Jablonowska, K. Lundin, A. Pinborg, and C. Bergh
Predictors of ongoing implantation in IVF in a good prognosis group of patients
Hum. Reprod., July 1, 2005; 20(7): 1876 - 1880.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. K. Omland, T. Abyholm, P. Fedorcsak, G. Ertzeid, N. B. Oldereid, S. Bjercke, and T. Tanbo
Pregnancy outcome after IVF and ICSI in unexplained, endometriosis-associated and tubal factor infertility
Hum. Reprod., March 1, 2005; 20(3): 722 - 727.
[Abstract] [Full Text] [PDF]

Home page
 Hum Reprod UpdateHome page
E. V. Younglai, A. C. Holloway, and W. G. Foster
Environmental and occupational factors affecting fertility and IVF success
Hum. Reprod. Update, January 1, 2005; 11(1): 43 - 57.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.