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Hum. Reprod. Advance Access published online on October 7, 2004
Human Reproduction, doi:10.1093/humrep/deh555
© 2004 by European Society of Human Reproduction and Embryology
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Debate

Cytoplasmic droplets: the good, the bad or just confusing?

T.G. Cooper 1*

1 Institute of Reproductive Medicine of the University Clinic, Münster, Domagkstrasse 11, D-48129 Münster, Germany

* To whom correspondence should be addressed. E-mail: cooper{at}uni-muenster.de.


  Abstract

The term cytoplasmic droplets is used to mean two different structures by basic scientists and clinicians. The literature on the presence, position and loss of cytoplasmic droplets and their relationship to infertility in animal species is reviewed. It is proposed that a change in terminology is required: ‘cytoplasmic droplet’ should be used to describe normal droplets associated with functional sperm produced by normal spermatogenesis and ‘excess residual cytoplasm’ is suggested to describe abnormal droplets associated with dysfunctional sperm that are products of faulty spermatogenesis.

Keywords: cytoplasmic droplet; excess residual cytoplasm; spermatogenesis.
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