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Hum. Reprod. Advance Access published online on September 9, 2005

Human Reproduction, doi:10.1093/humrep/dei299
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© The Author 2005. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.
Received May 31, 2005
Revised June 27, 2005
Accepted July 4, 2005

Article

Temporary uterine artery occlusion for treatment of menorrhagia and uterine fibroids using an incisionless Doppler-guided transvaginal clamp: Case report

G.A. Vilos 1*, E.C. Vilos 1, W. Romano 2, and B. Abu-Rafea 1

1 Department of Obstetrics and Gynecology, University of Western Ontario, St Joseph’s Health Care, London, Ontario, Canada
2 Department of Radiology, University of Western Ontario, St Joseph’s Health Care, London, Ontario, Canada

* To whom correspondence should be addressed.
G.A. Vilos, E-mail: george.vilos{at}sjhc.london.on.ca


   Abstract

We report the successful treatment of a 43-year-old woman with menorrhagia and multiple uterine fibroids by temporary uterine artery occlusion. Using a Doppler-guided transvaginal clamp, her uterine arteries were non-invasively identified and occluded by mechanical compression against the cervix for 6 h. Following removal of the clamp, blood flow in the uterine arteries returned immediately. Menorrhagia symptoms were tracked with the Ruta Menorrhagia Severity Scale. Uterine and fibroid volumes were measured by analysis of magnetic resonance images. The patient’s self-reported menorrhagia symptoms were significantly reduced at 6 months (70% reduction in Ruta score) and both uterine volume and fibroid volume had decreased by more than 44% at 6 months. This case report illustrates the potential applicability of a simple-to-use, non-surgical device for the treatment of menorrhagia and uterine fibroids by temporary uterine artery occlusion.

Keywords: fibroid/leiomyoma/menorrhagia/uterine artery occlusion.
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