Skip Navigation



Hum. Reprod. Advance Access published online on January 12, 2006
Human Reproduction, doi:10.1093/humrep/dei471
This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
21/5/1218    most recent
dei471v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Mercé, L. T.
Right arrow Articles by Villa, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mercé, L. T.
Right arrow Articles by Villa, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received October 4, 2005
Accepted December 2, 2005

Article

Assessment of the ovarian volume, number and volume of follicles and ovarian vascularity by three-dimensional ultrasonography and power Doppler angiography on the HCG day to predict the outcome in IVF/ICSI cycles

Luis T. Mercé 1 *, Santiago Bau 1, María J. Barco 2, Juan Troyano 3, Rosina Gay 4, Florencia Sotos 4, and Amelia Villa 4

1 Assisted Reproduction Unit, International Ruber Hospital, Madrid, Spain
2 University Clinic "Lozano Blesa", Zaragoza, Spain
3 University Hospital in La Laguna, Tenerife, Spain
4 IVF Laboratory, International Ruber Hospital, Madrid, Spain

* To whom correspondence should be addressed.
Luis T. Mercé, E-mail: ltmerce{at}segotex.es


  Abstract

OBJECTIVE: The aim of this prospective study was to investigate whether ovarian blood flow is related to embryological parameters and whether it could be a predictor of outcomes of IVF/ICSI. METHODS: Eighty infertile women underwent ovarian stimulation with gonadotrophins after a long protocol with GnRH agonists. The ovarian volume (OV), number of follicles (NF) and follicular volume (FV) of all follicles >10 mm and vascularization index (VI), flow index (FI) and vascularization-flow index (VFI) were obtained by three-dimensional (3D) ultrasonography and power Doppler angiography (PDA) on the day of HCG administration. These parameters were tested for their relation with IVF laboratory parameters. RESULTS: The OV, FV, VI, FI and VFI were significantly greater in the pregnant group. The NF and FV were the only independent predictors of the number of oocytes retrieved, mature and fertilized, and the number of embryos developed and their cumulative embryo score. Nevertheless, the number of grade 1 embryos depends on the NF and the VI. The ovarian FI and the number of transferred grade 1 embryos can predict gestation in 76% of IVF patients. A low FI and non-grade 1 embryo transferred are also associated with an increased pregnancy loss. CONCLUSION: 3D ultrasonography and PDA allow for an easier ovarian assessment in IVF cycles. The predictive value of IVF outcome suggests a high clinical usefulness of this new technique.

Keywords: blood flow/embryo quality/IVF-ICSI outcome/oocyte quality/3D ultrasound.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Ultrasound MedHome page
J. L. Alcazar, M. Garcia-Manero, and R. Galvan
Three-Dimensional Sonographic Morphologic Assessment of Adnexal Masses: A Reproducibility Study
J. Ultrasound Med., August 1, 2007; 26(8): 1007 - 1011.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
A. T Grazul-Bilska, C. Navanukraw, M. L. Johnson, D. A Arnold, L. P Reynolds, and D. A Redmer
Expression of endothelial nitric oxide synthase in the ovine ovary throughout the estrous cycle.
Reproduction, October 1, 2006; 132(4): 579 - 587.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.