Skip Navigation



Hum. Reprod. Advance Access published online on February 13, 2006
Human Reproduction, doi:10.1093/humrep/dei478
This Article
Right arrow FREE Full Text (PDF ) Freely available
Right arrow All Versions of this Article:
21/5/1227    most recent
dei478v1
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Perquin, D.A.M.
Right arrow Articles by Helmerhorst, F.M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Perquin, D.A.M.
Right arrow Articles by Helmerhorst, F.M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received May 4, 2005
Revised November 15, 2005
Accepted December 1, 2005

Article

Routine use of hysterosalpingography prior to laparoscopy in the fertility workup: a multicentre randomized controlled trial

D.A.M. Perquin 1 *, P.J. Dörr 1, A.J.M. de Craen 2, and F.M. Helmerhorst 3

1 Department of Obstetrics and Gynaecology, Medical Centre Haaglanden, The Hague, The Netherlands
2 Department of Gerontology and Geriatrics, Division of Reproductive Medicine, Leiden University Medical Centre, Leiden, The Netherlands
3 Department of Gynaecology, Division of Reproductive Medicine, Leiden University Medical Centre, Leiden, The Netherlands

* To whom correspondence should be addressed.
D.A.M. Perquin, E-mail: dperquin{at}knoware.nl


  Abstract

BACKGROUND: A multicentre randomized controlled trial with or without hysterosalpingography (HSG) was conducted to assess the usefulness of HSG as a routine investigation in the fertility workup prior to laparoscopy and dye. METHODS: From 1 April 1997 to 1 April 2002, subfertile women were allocated by a computer-based 1 : 1 ratio randomization procedure, either for an HSG followed by laparoscopy and dye (the intervention group) of for lapar-oscopy and dye only (the control group) as a part of their fertility workup. Cumulative pregnancy rate (CPR) within 18 months after randomization was the primary outcome of interest. RESULTS: 344 women were randomized to the intervention group (n = 169) and the control group (n = 175). There was no significant difference in CPR at 18 months in the intervention group (49.1%) [95% confidence interval (CI) 41.6 to 56.6] and the control group (50.3%) (95% CI 42.8 to 57.8), a difference of -1.2% (95% CI -11.8% to 9.5%). CONCLUSION: The routine use of HSG at an early stage in the fertility workup prior to laparoscopy and dye does not influence CPR, compared with the routine use of laparoscopy and dye without HSG.

Keywords: hysterosalpingography/laparoscopy and dye/pregnancy rate/randomized controlled trial.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
J.E. den Hartog, C.M.J.G. Lardenoije, J.L. Severens, J.A. Land, J.L.H. Evers, and A.G.H. Kessels
Screening strategies for tubal factor subfertility
Hum. Reprod., August 1, 2008; 23(8): 1840 - 1848.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
S.F.P.J. Coppus, B.C. Opmeer, F. van der Veen, P.M.M. Bossuyt, and B.W.J. Mol
Routine use of hysterosalpingography prior to diagnostic laparoscopy in the fertility workup
Hum. Reprod., October 1, 2006; 21(10): 2725 - 2726.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.