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Hum. Reprod. Advance Access published online on February 14, 2006

Human Reproduction, doi:10.1093/humrep/del022
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received October 5, 2005
Revised January 6, 2006
Accepted January 13, 2006

Article

Baseline dimensions of the human vagina

Kurt T. Barnhart 1 *, Adriana Izquierdo 2, E. Scott Pretorius 3, David M. Shera 4, Mayadah Shabbout 4, and Alka Shaunik 1

1 Penn Fertility Care, Department of Obstetrics and Gynecology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
2 Department of Internal Medicine, University of California, San Francisco, CA, USA
3 Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA
4 Children’s Hospital of Philadelphia, Philadelphia, PA, USA

* To whom correspondence should be addressed.
Kurt T. Barnhart, E-mail: kbarnhart{at}mail.obgyn.upenn.edu


   Abstract

BACKGROUND: Vaginal anatomy has been poorly studied. This study aimed to measure baseline dimensions of the undistended vagina of women of reproductive age. METHODS: We combined baseline information collected from five clinical trials using magnetic resonance imaging (MRI) to quantify distribution of a vaginal gel. Seventy-seven MRI scans were performed on 28 women before gel application to establish baseline vaginal measurements. Average dimensions were calculated for each woman and for the population. The influence of potential covariates (age, height, weight and parity) on these dimensions was assessed. RESULTS: MRI measurements are reproducible. The SD surrounding the mean at each anatomical site, and with summary measurements, was significantly smaller with each subject compared with the population. Mean vaginal length from cervix to introitus was 62.7 mm. Vaginal width was largest in the proximal vagina (32.5 mm), decreased as it passed through the pelvic diaphragm (27.8 mm) and smallest at the introitus (26.2 mm). Significant positive associations were parity with vaginal fornix length, age with pelvic flexure width and the height with width at the pelvic flexure. CONCLUSION: No one description characterized the shape of the human vagina. Although there is variation among women, variables such as parity, age and height are positively associated with differences in baseline dimensions.

Keywords: microbicide/MRI/pelvic anatomy/vagina.
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