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Hum. Reprod. Advance Access published online on July 4, 2006
Human Reproduction, doi:10.1093/humrep/del231
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received March 31, 2006
Revised May 11, 2006
Accepted May 18, 2006

Article

Measuring quality of life in women with endometriosis: tests of data quality, score reliability, response rate and scaling assumptions of the Endometriosis Health Profile Questionnaire

Georgina Jones 1 *, Crispin Jenkinson 2, Nicola Taylor 3, Abbie Mills 4, and Stephen Kennedy 5

1 School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
2 Health Services Research Unit, Department of Public Health and Primary Care, University of Oxford, UK
3 School of Psychology and Sociology, Central Queensland University, Rockhampton, Australia
4 School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield
5 Nuffield Department of Obstetrics and Gynaecology, Women’s Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK

* To whom correspondence should be addressed.
Georgina Jones, E-mail: g.l.jones{at}sheffield.ac.uk


  Abstract

BACKGROUND: To test the data quality, scaling assumptions and scoring algorithms underlying the Endometriosis Health Profile-30 (EHP-30) questionnaire: a questionnaire developed to measure the health-related quality of life (HRQoL) of women with endometriosis. METHODS: A cross-sectional postal survey to 727 women with surgically confirmed endometriosis recruited from an existing genetic linkage study (OXEGENE), The National Endometriosis Society (NES), UK and the outpatient gynaecology clinics of the Women’s Centre, John Radcliffe Hospital, Oxford. Tests of data quality included secondary factor analysis, internal reliability consistency, descriptive statistics of the data, missing data levels, floor and ceiling effects and corrected item to total correlation scores. RESULTS: Six hundred and ten women (83.9%) returned the questionnaire. Secondary factor analysis verified the domain structure of the EHP-30. All 11 dimensions were internally reliable with Cronbach’s {alpha} scores ranging from 0.80 to 0.96. Missing response rates ranged from 0.2 to 1.3%, and all items were found to be most highly correlated with their own (corrected) scale. CONCLUSIONS: Results confirmed the factor structure, scoring and scaling assumptions of the questionnaire. The high rate of data completeness indicated that the EHP-30 was acceptable and understandable to the respondents, thereby verifying its suitability for measuring the HRQoL of women with endometriosis.

Keywords: data quality/endometriosis/quality of life.
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