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Hum. Reprod. Advance Access published online on February 15, 2008

Human Reproduction, doi:10.1093/humrep/den026
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© The Author 2008. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Use of the SF-36 questionnaire to predict quality-of-life improvement after laparoscopic colorectal resection for endometriosis

G. Dubernard1, R. Rouzier1, E. David-Montefiore1, M. Bazot2 and E. Darai1,3

1 Department of Obstetrics and Gynecology, Hôpital Tenon, AP-HP, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France 2 Department of Radiology, Hôpital Tenon, AP-HP, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France

3 Correspondence address. Tel: +33-1-56-01-73-18; Fax: +33-1-56-01-73-17; E-mail: emile.darai{at}tnn.ap-hop-paris.fr

BACKGROUND: Laparoscopic colorectal resection for endometriosis can improve quality of life (QOL), but the results vary widely from one woman to another. The aim of this study was to determine whether the preoperative results on the Physical Component Summary (PCS) and Mental Component Summary (MCS) subscales of the SF-36 questionnaire could predict the improvement in QOL after surgery.

METHODS: The predictive value of the subscales was first evaluated on a training set of 57 patients. A mathematical model, quantified with respect to discrimination and calibration was then applied to the validation set of 36 patients.

RESULTS: Women with preoperative PCS and MCS scores below 37.5 and 44.5, respectively, had 80.7% and 84.2% probabilities of seeing their scores improve after surgery, whereas women with preoperative scores above 46.5 and 47.5, respectively, had probabilities of 0% and 10.7% to improve their scores.

CONCLUSIONS: With our mathematical model, the postoperative improvement in QOL can be reliably predicted. This model should help to identify those women who are most likely to benefit from this major surgery.

Key words: colorectal endometriosis/laparoscopy/SF-36 health status/quality of life

Submitted on October 8, 2007; resubmitted on November 28, 2007; accepted on December 11, 2007.


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