Cover design The front cover of Human Reproduction shows examples of the relationship observed between metaphase II (MII) spindle and the first polar body in human oocytes. (A) MII spindle appears directly below the polar body. (B) MII spindle at 90 degrees from the first polar body. (C) Schematic illustration of proposed risk zones, the closer to the first polar body (top) the greater the risk of MII spindle damage (indicated by the red colour). For further details, see pp. 13721376.
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