The cover shows an example of spindle abnormalities in normally developing human blastocysts day 5 post insemination, identified immunohistochemically with antibodies to alpha-tublulin (red) and DAPI nuclear strain (blue). Several spindles in the mural trophectoderm can be seen including a tripolar spindle shown in higher magnification(insert). For further information please see Chatzimeletiou pp 672-682
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