The cover of Human Reproduction shows inhibition of proteasomal activity by immunological neutralization during bovine IVF. Panel A and A′ (controls) show normal pronuclear development and apposition - B and B′ (after transfection with anti-proteasomal antibody E446) show failure of the sperm aster formation and lack of pronuclear apposition. For further details see Rawe et al., pp. 573-580.
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